scientific instrumentation

Custom low‑field NMR spectrometers & hyperpolarization systems for modern research

CYPRUS AUTOMATION designs dedicated low‑field NMR spectrometers and xenon‑129 hyperpolarizers for biomedical imaging, chemistry, and materials science applications.[web:2][web:5]

Since 2016 in xenon‑129 hyperpolarization and low‑field NMR instrumentation.[web:2][web:5]
Focus — integrated, application‑specific devices for laboratories and clinical centers.[web:2][web:5]

About the company

CYPRUS AUTOMATION is an engineering company dedicated to xenon‑129 hyperpolarization and low‑field NMR instrumentation for research and clinical‑scale applications.[web:2][web:5]

Low-field NMR spectrometer system on the lab bench
Low‑field NMR spectrometer configured for xenon‑129 polarimetry near the hyperpolarizer.[web:2][web:5]
Close-up of the NMR detection coil and sample region
Detection coil and sample region for low‑frequency pulse‑and‑acquire NMR measurements.[web:2][web:5]

Focus on Xe‑129 hyperpolarization

The team builds batch‑mode spin‑exchange optical pumping (SEOP) hyperpolarizers and supporting quality‑control tools for hyperpolarized xenon‑129 production.[web:5][web:22]

Integrated low‑field NMR spectrometers

Compact low‑frequency NMR spectrometers are developed for polarimetry and relaxation measurements of hyperpolarized gases and contrast agents in the 1–125 kHz range.[web:2][web:5][web:47]

Custom, experiment‑driven devices

Systems are tailored to specific experimental protocols, from basic research setups to clinical‑scale Xe‑129 production and OEM modules for integration into larger platforms.[web:2][web:5]

Solution areas

The company covers the full development cycle — from system architecture and electronics to embedded firmware, control software, and on‑site commissioning.[web:2][web:5]

Integration of the low-field NMR spectrometer with a xenon hyperpolarizer
Example integration of a low‑field NMR spectrometer with a xenon‑129 hyperpolarizer and gas handling system.[web:5][web:22]

LF NMR spectrometers for polarimetry

Ultra‑low‑field, pulse‑and‑acquire NMR spectrometers optimized for in‑situ polarimetry of hyperpolarized Xe‑129 and other nuclei in SEOP hyperpolarizer setups.[web:2][web:5][web:47]

  • Pulse‑and‑acquire operation for polarimetry and relaxation measurements.[web:2][web:5]
  • Integration with NMR coils, heating jackets, field control, and gas handling modules.[web:2][web:5]
  • APIs and software for automated experiments and data export to existing analysis pipelines.[web:2][web:5]
LF NMR Polarimetry 129Xe

Xenon‑129 hyperpolarization systems

Batch‑mode and stopped‑flow Xe‑129 hyperpolarizers for lung MRI, molecular imaging, and fundamental NMR spectroscopy.[web:22][web:29][web:50]

  • SEOP‑based hyperpolarization using high‑power laser pumping.[web:22][web:29]
  • Quality assurance and delivery modules for HP Xe‑129 gas for research and clinical studies.[web:29][web:50]
  • Adaptation to specific MRI/NMR protocols and integration with imaging centers.[web:20][web:50]
HP Xe‑129 SEOP MRI

Parahydrogen and auxiliary systems

Parahydrogen generators and gas‑handling modules for PHIP, SABRE, and related MR hyperpolarization experiments.[web:29][web:31]

  • Parahydrogen production systems with configurable enrichment levels.[web:29][web:31]
  • Distribution and dosing modules for gas delivery to experimental setups.[web:29][web:31]
  • Integration with existing NMR/MRI infrastructure and safety systems.[web:29][web:31]
Parahydrogen Hyperpolarization

Technical expertise

The team combines experience in NMR physics, laser optics, RF electronics, and embedded control for robust, integrated instruments.[web:2][web:5][web:22]

Hardware platform

  • Design of low‑frequency NMR coils, RF front‑ends, and shielded enclosures for LF applications.[web:2][web:5][web:47]
  • Magnetic assemblies, gradient coils, and field‑control subsystems for SEOP and polarimetry.[web:5][web:22][web:50]
  • ARM STM32‑based embedded control for fully automated hyperpolarizers and spectrometers.[web:5]

Software & automation

  • Control software for Xe‑129 hyperpolarizers, low‑field NMR spectrometers, and gas‑handling modules.[web:2][web:5][web:47]
  • Tools for acquisition, visualization, and export of NMR data and polarization metrics.[web:2][web:5][web:47]
  • Integration with laboratory information systems and existing analysis environments.[web:2][web:5]

Scientific collaboration

  • Joint definition of experimental protocols and system requirements with academic and clinical partners.[web:2][web:5][web:20]
  • On‑site commissioning, user training, and remote technical support for installed systems.[web:2][web:5][web:20]
  • Long‑term service, upgrades, and custom module development for new studies.[web:2][web:5][web:20]

Contact

Share a short outline of your project, and the team will propose an instrument architecture and collaboration format for your lab or imaging center.[web:2][web:5]

E‑mail: info@cyprus-automation.com
Project domains: Xe‑129 hyperpolarization, low‑field NMR, HP MRI, parahydrogen systems.[web:2][web:5][web:22][web:29]
Typical partners: university labs, research institutes, clinical centers, and industrial R&D groups.[web:2][web:5]

Provide a brief description of your application, and CYPRUS AUTOMATION will follow up to discuss technical requirements.